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Stem cell therapy for knee cartilage repair without surgery

Stem cell therapy for knee cartilage repair and regeneration without surgery in India

Annie is from Nigeria, She is a working lady with 2 pretty daughters, a husband, and parents. She is managing her office and home perfectly. 

One thing which worries Annie is that her mother has been suffering from knee pain for the past 5 years and the condition of her mother’s knees is deteriorating day by day and pain is increasing severely. Even the painkiller is not getting effective. 

She is not able to do day to day life work because of her knee pain. She loves to play with her grandchildren but her knee restricts her joy. 

Annie has shown her mother to many doctors, they suggested she do knee replacement surgery for her mother.

Annie’s mother, a 62 years old lady afraid to go for knee replacement surgery, said a straight NO to her. Even trying to convince her mother she denied doing so.  Annie had no other option left besides stem cell therapy for knee cartilage repair without surgery.

knee replacement surgery

One holiday Annie was surfing the internet for alternative treatment for knee pain. She read about stem cell therapy, she is reading more and more from different sources about stem cells. She eventually visited the MedicoExperts website and read a blog about stem cell treatment and decided to leave an inquiry. 

MedicoExperts patient care executive got in touch with Annie, she narrated the condition of her mother and also forwarded some reports which she did. All the information regarding treatment, how the procedure is going to be done is conveyed.

Then a video consultation is done and the doctor tells them regarding the treatment as it is not surgery her mother is also convinced to do the treatment.

Next week they decided to come and got admitted to the hospital. The treatment started and 2 doses of stem cells were given to her mother.

Within a week pain in her knee decreased drastically that she is not taking any painkillers. After 3 weeks she is able to walk again without any support with a knee bandage to support.

Currently, she is able to walk without a knee bandage. 

Let’s understand that what knee pain is and why it occurs.

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knee pain

What is knee pain?

Knee pain occurs when wear and tear happen in the knee. It can happen to people of any age, most common in old age. 

Commonly knee pain is the result of an injury, such as a ruptured ligament or torn cartilage. Cartilage is the flexible connective tissue on the ends of the bone.  

Medical conditions such as arthritis, gout, lupus, and infections also can cause knee pain.

Physical therapy and knee braces help in relieving minor pain. In some cases, however, your knee may require surgical repair apart from surgical alternative treatment options are also available.

knee pain treatment
sign and symptoms of knee pain


What are the sign and symptoms of knee pain?

The location and severity of the knee pain can vary depending on which location the knee is damaged.

Infection or an inflammatory process: The whole knee might be swollen and painful. 

Torn meniscus or fracture of a bone: Gives symptoms only in one specific location of the knee. 

Baker cyst: Typically causes pain in the back of the knee.

Some of the signs and symptoms that go along with knee pain include:

  • Swelling and stiffness
  • Redness and warmth to the touch
  • Weakness or instability
  • Popping or crunching noises
  • Inability to fully straighten the knee
  • Unable to bend the knee

Now we have understood the signs of knee pain let’s understand some common causes.

What are the most common causes of knee pain?

Below is a list of some of the common causes of knee pain.

Injury is the common cause of knee pain. It can affect ligaments, bones, tendons (which is a soft tissue that connects muscle to the bone), fluid-filled sacs(bursae) that surround the knee. 

Knee injuries include:

  • ACL injury: An ACL (anterior cruciate ligament) injury is a tear or sprain of the ACL, one of the strong bands of tissues that connect your shinbone(tibia) to your thighbone(femur). Typically ACL injury occurs to the people who play sports that require sudden changes in direction. 
  • Fractures: Accident is the common cause of the fracture in which the bones of the knee, including the kneecap (patella), can be broken. Osteoporosis can also cause knee fracture simply by stepping wrong because it is a disease that weakens the bone.
  • Torn meniscus: The meniscus (c-shaped, tough rubbery cartilage) acts as a shock absorber between your shinbone(tibia) and thighbone(femur). This can happen when you suddenly twist your knee while lifting a heavyweight.
  • Knee bursitis: Knee injuries that cause inflammation in the bursae which are small sacs of fluid that cushion the outside of your knee joint so that tendons and ligaments glide smoothly over the joint.
  • Patellar tendinitis: Tendinitis causes irritation and inflammation of one or more tendons (the thick, fibrous tissues that attach muscles to bones). This inflammation can happen when there’s an injury to the patellar tendon, which runs from the kneecap (patella) to the shinbone and allows you to kick, run and jump. Typically sports and activities may develop patellar tendinitis includes running and jumping.

Mechanical problems that cause knee pain includes:

  • Loose body: Sometimes, injury or degeneration of bone or cartilage can cause a piece of bone or cartilage to break off and float in the joint space. A loose body may not create any problems unless it interferes with knee joint movement; the effect is something like a pencil caught in a door hinge.
  • Iliotibial band syndrome: It’s a long piece of connective tissue that extends from outside of your leg from the hip to the knee and shinbone. Overuse and repetitive bending of the knee and extension of the knees usually cause this type of injury. 
  • Dislocated kneecap. This occurs when the triangular bone that covers the front of your knee (patella) slips out of place, usually to the outside of your knee. In some cases, the kneecap may stay displaced, and you’ll be able to see the dislocation.
  • Hip or foot pain. If you have hip or foot pain, you may change how you walk to spare your painful joint. But this altered gait can place more stress on your knee joint and cause knee pain.

Some variety of arthritis most likely to affect the knee include:

  • Osteoarthritis: Osteoarthritis is degenerative arthritis, osteoarthritis is the most common type of arthritis. In this condition wear-and-tear occurs when the cartilage in your knee deteriorates with use and age.
  • Rheumatoid arthritis: Rheumatoid arthritis is a chronic disease, it tends to vary in severity or may even come and go. It usually weakens the joints, rheumatoid arthritis is an autoimmune condition that can affect almost any joint in your body, including your knees. 
  • Gout: It occurs when too many uric acid crystals build up in the joint. While gout most commonly affects the big toe, it can also occur in the knee.
  • Pseudogout: Pseudogout is caused by calcium-containing crystals that develop in the joint fluid. Knees are the most common joint affected by pseudogout. These calcium deposits cause inflammation in the knee.
  • Septic arthritis: Septic arthritis is an infection in knee joints, that can come through germs that can travel through your bloodstream. Leading to swelling, pain, and redness. Septic arthritis can quickly cause extensive damage to the knee cartilage. If you have knee pain with any of the symptoms of septic arthritis, see your doctor right away.

Patellofemoral pain syndrome: It is a condition in which cartilage under the knee cap is damage. It’s common in athletes; in young adults, especially those whose kneecap doesn’t track properly in its groove; and in older adults, who usually develop the condition as a result of arthritis of the kneecap.


Knee pain diagnosis and tests


Physical examination:

  • The doctor will Inspect your knee for swelling, pain, sensitivity to pain, warmth, and visible bruising
  • The doctor will check your knee movement
  • Evaluate the integrity of the structures in your knee

Imaging tests:

In some of the imaging tests were:

  • X-ray: X-ray, will help to detect bone fractures and degenerative joint disease.
  • Computerized tomography (CT) scan: CT scans can help diagnose bone problems and subtle fractures. A special kind of CT scan can accurately identify gout even when the joint is not inflamed.
  • Ultrasound: This technology uses sound waves to produce real-time images of the soft tissue structures within and around your knee. Your doctor may want to move your knee into different positions during the ultrasound to check for specific problems.
  • Magnetic resonance imaging (MRI): An MRI is particularly done to identify injuries of the soft tissues such as ligaments, tendons, cartilage, and muscles.

Now let’s understand treatment options for knee pain

knee xray

Conventional treatment for knee pain and cartilage regeneration in India

Treatments will vary, depending upon the severity and causes.

Medications to help relieve pain and to treat the conditions causing your knee pain, such as rheumatoid arthritis or gout.

Physical therapy or different types of strengthening exercises based on the specific condition that is causing your pain is done to strengthening the muscles around your knee will make it more stable.

Corticosteroids: Injections of a corticosteroid drug into your knee joint may help reduce the symptoms of an arthritis flare and provide pain relief that may last a few months. These injections aren’t effective in all cases.

Hyaluronic acid: A thick fluid, similar to the fluid that naturally lubricates joints, hyaluronic acid can be injected into your knee to improve mobility and ease the pain. 

Platelet-rich plasma (PRP): PRP contains a concentration of many different growth factors that appear to reduce inflammation and promote healing. Some studies have found that PRP may benefit certain people with osteoarthritis, but more studies are needed.

If you have an injury that may require surgery, it’s usually not necessary to have the operation immediately. Before making a decision, consider the pros and cons of both nonsurgical rehabilitation and surgical reconstruction in relation to what’s most important to you. If you choose to have surgery, your options may include:

Arthroscopic surgery: Depending on your injury, your doctor may be able to examine and repair your joint damage using a fiber-optic camera and long, narrow tools inserted through just a few small incisions around your knee. Arthroscopy may be used to remove loose bodies from your knee joint, remove or repair damaged cartilage (especially if it is causing your knee to lock), and reconstruct torn ligaments.

Partial knee replacement surgery: In this procedure, your surgeon replaces only the most damaged portion of your knee with parts made of metal and plastic. The surgery can usually be performed through small incisions, so you’re likely to heal more quickly than you are with surgery to replace your entire knee.

Total knee replacement: In this procedure, your surgeon cuts away damaged bone and cartilage from your thighbone, shinbone, and kneecap, and replaces it with an artificial joint made of metal alloys, high-grade plastics, and polymers.

Osteotomy: This procedure involves removing bone from the thighbone or shinbone to better align the knee and relieve arthritis pain. This surgery may help you delay or avoid total knee replacement surgery.

Stem cell therapy for knee cartilage repair without surgery

stem cell therapy for knee cartilage repair without surgery

Stem cells are the basic building blocks of our body with the characteristic of dividing themselves and multiply their numbers.

These cells can develop into different types of cells with a specific function depending on where they are placed. 

For example, when stem cells are placed near damaged cartilage, they can transform themselves into cartilage tissue later on.

Mesenchymal Stem Cells are the common types of stem cells that are used for treating Arthritis. These cells are collected or harvested from the fat, blood, or bone marrow of the patient.

Knee stem cell therapy is a relatively newer alternative method for knee joint pain treatment. This approach to knee joint pain treatment has more advantages when compared to the traditional approaches.

This therapy extracts the unique type of cells in our body called the stem cells, usually from an area of high density, and then injects them into the damaged area to help the body heal naturally.

 Let’s understand the procedure of stem cell therapy for knee pain.


Procedure for stem cell therapy for knee pain and cartilage regeneration in India

Stem cell therapy is a simple and completely safe procedure that requires only injections and no surgery is involved. In Stem cell procedure, Adult stem cells are taken from the bone marrow of the patient and injected back into the patient after processing them in a specialized stem cell laboratory.

The procedure involves 3 steps.

Step1: Bone Marrow Aspiration:

In this process, a needle is inserted into the hip bone to extract the bone marrow. This is done under local anesthesia so that the patient does not experience pain. 

Step 2: Stem Cell Separation:

The bone marrow which is taken in step 1 from the patient is sent to the Stem cell laboratory, where the stem cells are separated from the remaining cells of the bone marrow by the density gradient method.

Step 3: Stem Cell Injection:

Stem cells are injected back into the infected areas.

hip pain treatment without surgery
prerequisites of stem cell therapy

Who is the Ideal candidate for stem cell therapy for knee pain and cartilage regeneration treatment in India?

Stem Cell Therapy does not have a restriction on who can receive the treatment.

Stem Cell Therapy is recommended for the following cases:

  • Patients with early arthritis.
  • Young patients with mild osteoarthritis or cartilage damage
  • Healthy patients with relatively less cartilage damage

Stem Cell therapy can help treat patients suffering from the following knee injuries and conditions:

  • Early arthritis / Osteoarthritis
  • Meniscus Tear
  • MCL, ACL, PCL, and LCL tears and sprains
  • Knee Instability
  • Patellofemoral Syndrome
  • Traumatic knee injury

What are the expected outcomes of stem cell therapy for cartilage repair in India?

  • Repair damaged cartilage
  • Slow the deterioration of cartilage
  • Decrease inflammation and reduce pain
  • Possibly delay or prevent the need for knee replacement surgery
  • Reduce pain, even chronic joint pain, with less need for medications.
  • Increase functionality, range of motion, and flexibility.
  • Reduce muscle compensations and risk for future injuries
  • Decrease nerve damage
  • Return patients to their normal activities as quickly as possible
knee pain recovery outcome, stem cell therapy for knee pain
iui treatment in india

Treatment Cost

Cost of stem cell therapy for knees treatment in India

India is one of the most cost-effective and result-oriented destinations to choose to undergo stem cell therapy. With the availability of state-of-the-art hospitals, the best stem cell experts, and excellent infrastructure which is at par with international standards, you also get affordability and trustworthiness.

The stem cell therapy for knee pain treatment in India is based on the patient’s requirements and medical condition.

The cost of stem cell therapy in India starts from USD 2000 per cycle, depending on the patient’s current condition, treating doctor, and suggested treatment protocol. A stay of 12-15 days in the country is required for the entire treatment, and in some cases, the stay may be extended to 45 days as well.

Frequently Asked Questions and patient concerns:

1. Does stem cell therapy for knees really work?

Studies have shown that stem cell therapy can help reduce knee pain and improve function.

2. How much does stem cell therapy for knees cost?

Stem cell therapy for knees cost is cover above.

3. What happens if you don't do a knee replacement?

The longer patients wait and allow their knee issues to affect them, the more it impacts overall health. It may become harder to walk, drive, and do household chores.

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