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Intrauterine Insemination

Everyone’s journey to becoming a parent is special and diverse, but we all are planning for the same goal and that is to have a baby! But infertility is a condition that makes it harder, and often impossible, to get pregnant without medical assistance. Thanks to modern medical science, a number of infertility treatments are currently available to help you conceive including the high-tech assisted Reproductive technology (ART). This assisted reproductive technology has 3 options comprising of IUI, IVF and ICSI .

With so many treatment options to choose from, couples are able to find a way to overcome their infertility, achieving the goal of one day having a family of their own. IUI commonly known as called an Intrauterine Insemination or Artificial Insemination is one such simple and first line treatment option when medication and natural method of conception does not succeed.

Intrauterine Insemination (IUI) is a fertility treatment where a processed sperms are directly into a women’s uterine cavity through cervix around the time of ovulation. Talking about the natural conception, the sperm have to travel from vagina through cervix, into a uterine cavity and reach fallopian tube to fertilize the egg. However in IUI, semen sample taken from the male partner is processed in the laboratory to make it concentrated with the motile sperms and then injected directly into uterus, which puts them closer to the egg. This entire process increases the likely chances of pregnancy in couples who have been facing problems to conceive.

Few things are requisite for going ahead for IUI as a treatment option, those are :

  • A female should be ovulating either with or without assistance of medication.
  • Fallopian tubes should be normal and patent.
  • Sperm count in male should be either normal or mild to moderately decrease.


IUI is usually a non-invasive and very less-expensive treatment option for fertility when compared to a more invasive option like IVF and ICSI. It is not indicated for all the couples facing infertility issues. It is most commonly used if a female or male is being suffering from one of the following conditions.

  • Mild endometriosis
  • Problems with cervix or cervical mucus
  • Unexplained infertility
  • Low sperm count
  • Diminished Sperm Motility
  • Issues with ejaculation
  • Erectile Dysfunction
  • A single fertile women who wish to conceive
  • A couple who wants to avoid passing on a genetic defect from a male partner to child


After undergoing the fertility assessment, your doctor may suggest you the appropriate option for conceiving. When you undergoing IUI procedure, following are the steps you can expect to go through for successful conception.

Step 1: Pre IUI Work-up
Before proceeding with the IUI procedure, you will need to undergo comprehensive pre-IUI work up to check if you are completely healthy. This is also done to assess your hormone levels to check if they are in a normal range and confirm that if your uterus can support a pregnancy or no.

Step 2: Monitoring of Ovulation
After the work up, if there seems to be the hormonal imbalance, the specialist may put you on ovulation drugs, while they will closely monitor your ovulation by timed ultrasound and blood testing. This will confirm that you are producing healthy eggs. This will also assist the specialist to decide the best time to inject sperm into the uterus.

Infertility Treatment in India

Step 3: Preparation of Semen Sample
Your partner will need to give a semen sample for processing it in the laboratory to concentrate it with the motile and viable sperm and prepare it for IUI. This process also helps in removing the potentially toxic chemicals that may be present in the semen to which a female body may react negatively. Processing of the sperms in a standardized way helps the healthiest and most motile sperm to reach the egg thereby increasing the success rate of IUI.

Step 4: Sperm Insertion
This prepared sperm sample is then injected into the women’s uterine cavity through cervix. Injecting a prepared sperm into uterus is usually a quick and painless procedure. This is done by making women lie on examination table as they do for pelvic examination. The specialist will then insert a very small, flexible and thin catheter into cervix through which the processed sperm sample is injected directly into the uterus.

Step 5: Follow up after IUI
After successful IUI procedure, your specialist will see you regularly to keep a check on your progesterone levels. The specialist will also observe your uterine lining by doing regular ultrasound test. The thickness and composition of this uterine lining will suggest to whether the IUI procedure was effective. After approximately 14 days, a blood test is done which confirm the pregnancy.

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Are you a Candidate?

Intrauterine Insemination (IUI) is a relatively simple fertility treatment option which can be done with or without fertility drugs. You may be considered as a good candidate for IUI procedure if you are facing any of the following situations.

  • Unexplained infertility
  • Male infertility due to low sperm count or moderately diminished motility of the sperms
  • Erectile dysfunction in males or problems with ejaculation
  • If conception has not been successful in spite of treatment with fertility drugs
  • Problems during intercourse like sexual pain which makes intercourse not possible
  • Hostile cervical mucus

Expected Results

After an IUI procedure, your specialist will put you on some medications which include progesterone necessary for creating a required environment in the uterus for embryo implantation.

After 10-14 days post IUI procedure, you will need to undergo a pregnancy blood test.

The success rates of IUI procedure will vary depending upon the individual’s cost of infertility and age of the couple. The success rates are relatively higher if the couple undergoes multiple cycle of IUI together rather than a single one.

Recovery Timeline

Being a very simple and small procedure, it does not require much of your time. You need to be in India for a period of just 2-3 weeks. You would need to plan to visit the fertility specialist at least a week prior the scheduled dates of female partner’s periods.

The entire procedure is done on outpatient basis and no hospitalization is required.

Treatment cost

Cost of IUI Procedure

India is one of the most affordable places for Infertility treatment across the globe. We certainly understand that if you have chosen to travel overseas for your IUI procedure, then you are indeed looking for cost effectiveness. When you speak about the best, MedicoExperts is the name you can trust on.

Modern technology, State of the art hospitals, most coveted gynecologist and fertility specialists, excellent infrastructure at par with international standards, no language barrier, personalized attention, safe surgery and seamless travel are some of our zeniths which magnetizes individuals worldwide to get their Infertility treatment in India done through us.

We are thus committed to offer you the best possible and special negotiated prices for your IUI procedure without compromising on the quality of medical services and results. Here’s a look at the approximate costs of IUI procedure in India:

Sr.No. Name of Procedures Cost of Procedure USD
1 IUI Evaluation Package 400-800
2 Intrauterine Insemination (IUI) 500-700
3 Intrauterine Insemination (IUI) with Donor Sperm 1000-1500

Frequently Asked Questions and patient concerns:

1. What Is Intrauterine Insemination (IUI)?

A relatively straightforward fertility treatment is IUI, or intrauterine insemination. It can be achieved with fertility medications or without them. The process itself requires the transfer, via a thin catheter, of semen which has been treated and concentrated directly into the uterus. To increase the chance of pregnancy, IUI is performed at the time of ovulation or in combination with fertility drugs.

2. Who can benefit from IUI Treatment?

Generally, where medicine and timed intercourse do not work, IUI is the first line of treatment. It is recommended in patients with minor to severe declines in sperm count and/or sperm motility, or if endometriosis is mild. Ovulation induction can be paired with IUI for females who do not ovulate frequently. IUI can also be recommended for those spouses who do not have any clear cause of infertility (unexplained infertility).

3. When is it ideal to get an IUI treatment done?

An egg is only viable 24 hours after it is released. Before or after ovulation, the optimal time for IUI is 6 hours. If the IUI is to be timed according to the hCG dose, it is to be given 24 to 48 hours after the dosage of the injection. Usually, when two IUIs are scheduled, they are spaced at least 12 hours apart, ranging from 24 to 48 hours.

4. How long before IUI should the male abstain from intercourse?

This varies from person to person, but in order to maintain high motility and morphology, we generally prescribe 48 hours after the last ejaculate. We either suggest a delay of just over 48 hours if IUI is completed for borderline sperm count, or we call for an additional sample to be frozen, so that we could take sperm from 2 specimens.

5. How and where is the sperm collected?

In a clean collecting cup, preferably in the hospital, the male partner is asked to gather his ejaculate. Then the sperm is isolated from the semen and cleaned prior to insemination. As soon as sperm washing is done, IUI is carried out. This helps improve the rate of success.

6. How successful is this treatment approach?

Worldwide, the average IUI success rate is around 15 per cent. Within the first three IUI stages, about 80 percent of conceptions take place. Usually, we prescribe a maximum of three cycles of IUI.

7. What is it like to undergo an IUI?

IUI is a painless treatment for nearly all females, and it feels the same as when you have a pap smear test done. As the cervix is partially exposed due to ovulation, no pain is caused by the catheter that is inserted to transfer the sperm. Later on, some women may experience some cramping, but it is mostly due to ovulation.

8. How long does a sperm live?

Sperms live for up to 48 hours. They gradually start losing their potency after 24 hours.

9. Do I have to lay down after IUI?

After the sperm transfer, you could be asked to lie down for 15-30 minutes. As the semen just moves forward and the cervix ix shuts, immediately after that, people can walk and head back home.

10. Is there a possibility that the sperm can fall out of the uterus?

This is a very common question posed by many couples, not only for IUI, but also for normal intercourse. And the answer is no, the sperm only travels forward after insemination. You may however feel damp, but that is largely due to the small volume of semen coming out of the cervix.

11. Is there any bleeding after IUI?

No, bleeding is not typical, but either due to the method or ovulation, there is a possibility you could see a few drops.

12. Is it necessary to rest after IUI?

IUI is a very straightforward treatment, and if there is slight cramping or feeling any pain, we suggest that you take it slow after that. It is crucial to watch for personal signs and act accordingly. It can help improve the chances of implantation by stopping strenuous workouts and preventing heavy lifting.


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