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IVF

IVF Treatment

Every couple desire to start a family but in some cases they are unable to conceive due to infertility. They keep trying for years, anticipating successful conception without any treatment but the results are rather upsetting. There are numerous medical conditions that may contribute to infertility in both men and women. The signs and symptoms may differ in each case. Infertility is a very common problem and most of people consider this condition a taboo and are hesitant to talk about it. But thanks to the advancement in the medical technology, infertility can be treated successfully with several promising treatment options including In Vitro Fertilization (IVF).

In vitro fertilization, commonly called as IVF, is a type of assistive reproductive technology (ART) and is defined as a multifaceted series of procedures accustomed to treat infertility of genetic problems and assist couples with the conception of a child. In this, the mature eggs are collected from ovaries of a woman and fertilized by sperms in a specialized laboratory. This fertilized egg which is called as embryo is implanted in women’s uterus or it can be frozen for storage so as to use it for subsequent IVF cycles. It takes around two weeks for one cycle of IVF to complete. Depending on the couple’s condition, IVF can be done in the following variations –

  • IVF with your own eggs and your partner’s sperm.
  • IVF with your own eggs and a donor sperm.
  • IVF with donor eggs and your partner’s sperm.
  • IVF with donor eggs and a donor sperm.

Causes

In vitro fertilization (IVF) is an invasive treatment done to treat couples with infertility and who wants to have a baby. A couple may try the other less invasive treatment options for infertility before opting for IVF.

These options comprises of fertility medications meant to increase production of eggs or IUI (Intrauterine Insemination) wherein sperms are placed directly in woman’s uterus during the ovulation period.

In some cases though, IVF can be considered as a primary treatment option for infertility. Besides, it can also be done if you or your partner is suffering from certain health conditions including the following:

blocked fallopian tube treatment in india
  • Ovulation disruptions : Disturbance in the ovulation owing to infrequent, irregular or absent menstrual cycle results in lesser number of eggs available for fertilization.
  • Fallopian tube blockage or damage : Blockage or impairment in the fallopian tubes makes it difficult for an egg to get fertilized or for a fertilized embryo to propagate through tube to the uterus.
  • Premature Ovarian failure : It is termed as loss of normal ovarian function before women turns 40 years of age. In such cases, the ovaries fail to produce normal amount of estrogen hormone and to release matured egg regularly.
  • Uterine fibroids : These are the benign tumors present in the wall of the uterus and are most common in females in their 30’s and 40’s. Presence of fibroids may interfere with the implantation of fertilized embryo in the wall of uterus.
  • Endometriosis : This occurs with the uterine wall tissues starts growing outside the uterus thereby affecting the normal functioning of ovaries, fallopian tubes and uterus.
  • History of tubal sterilization or removal : Tubal ligation is a type of sterilization procedure wherein the fallopian tubes are either blocked or cut to permanently prevent pregnancy. In such cases, if the female wish to conceive, IVF can be an alternative solution rather than a tubal ligation reversal procedure.
  • Impaired sperm production or function : It becomes difficult for a sperm to fertilize an egg if the male semen has below average sperm concentration, poor mobility or abnormalities in size and shape of the sperm. In cases of abnormalities, the male need to be evaluated to determine if the underlying problems can be corrected.
  • Unexplained infertility : In cases where there has been no known cause of infertility in spite of doing all the evaluations, IVF can be the solution.
  • Fertility Preservation for cancer or other health issue : If women is diagnosed with cancer and is supposed to start the treatment like chemotherapy or radiation therapy which could harm her fertility, then IVF for fertility preservation may be an option. In this, women can have her eggs harvested from the ovaries and freeze it in an unfertilized state or as an embryo for future use.

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Procedure

As mentioned earlier, IVF is an effective type of assistive reproductive technology (ART) which comprises of multifaceted series of procedures. There are six basic phases of an IVF cycle. Each phase has been explained in details below.

This phase of IVF may not be practiced in every case. The suppression of your pituitary gland and ovaries are done a month prior to your scheduled egg retrieval. In this, the fertility specialists use oral contraceptive pills shots to down-regulate your natural hormonal flow and take control of your ovarian stimulation with injectable fertility medications. By suppressing your pituitary and ovaries, we can minimize the formation of naturally occurring ovarian cysts. Also, the Follicle Stimulating Hormonal and Luteinizing Hormonal receptors on ovaries become more sensitive and thus require less injectable fertility medications to stimulate them.

Normally, a woman produces one egg during each menstrual cycle. However, for IVF we need multiple eggs since it increases the chances of developing a viable embryo. In order to achieve that, during the stimulation phase, a woman will be give daily injections of fertility medications for 9 to 11 days. This will boost the egg production and enables the ovaries to produce several eggs in one cycle. During this period, the fertility specialist will perform regular blood investigations and ultrasound so as to monitor the production of eggs and to determine the perfect time to retrieve them.

Egg retrieval also known as follicular aspirations is small surgical procedure performed under anesthesia. Under the guidance of ultrasound, the surgeon will pass a thin needle through the upper portion of vagina into your ovary and into an egg-containing follicle. This needle will then aspirate the eggs and fluid out of each follicle. The recovery after this procedure is usually rapid and you will be monitored for next 1 hour after the procedure before going home. Some women may experience mild cramping on the day of retrieval which usually subsides by the evening of retrieval.

In this phase, semen sample is taken from the male. The eggs are identified and isolated from the follicular fluid and placed in an incubator. Later, these eggs are fertilized with sperm either by conventional insemination or Intracytoplasmic Sperm Injection (ICSI).

This egg is then monitored to document fertilization. Once fertilized, the egg starts dividing and develops into an embryo. The embryologist keeps a close check on embryo to make sure it matures properly. On day two or three after fertilization, the embryos will be evaluated for blastocyst culture. The embryos are then grown for five or six days until they reach the blastocyst stage.

This is a painless procedure in which the embryo is placed into the uterus through a highly specialized catheter under the guidance of ultrasound. No sedation is necessary for this procedure and is usually done 3-5 days after fertilization. After this embryo transfer, progesterone supplementation via injection or vaginal suppository will be given for next 10-12 days and a blood pregnancy test will be performed approximately 2 weeks after the egg retrieval date.

A successful pregnancy occurs when the embryo implants itself into uterine wall called as endometrium. This can take 6-10 days after embryo transfer phase. Then the initial pregnancy test is performed to determine if you are pregnant. Once the viability is confirmed, you will be referred the Obstetric and Gynecologist for appropriate prenatal care.

Are you a Candidate?

You can be considered for an IVF for getting pregnant If you are facing issues like ovulation disruptions, blocked fallopian tubes, endometriosis or uterine abnormalities. If your partner is also suffering from problems with sperm count and motility or if other fertility treatment have been unsuccessful, then you may be a good candidate for IVF treatment.

Expected Results

One cycle of IVF takes about 4-5 weeks to complete. The outcome of IVF varies considerably and depends on each couple’s reason for infertility. It also depends on the ages of the couple. Younger women usually have higher success rates.

Recovery Timeline

IVF is an invasive treatment for infertility comprising of steps like ovulation induction, egg retrieval, sperm retrieval, fertilization and embryo transfer. One cycle of IVF takes about 4-5 weeks to complete.

Cost of Infertility Treatment

India is one of the most affordable places for IVF treatment across the globe. We certainly understand that if you have chosen to travel overseas for your IVF treatment, then you are indeed looking for cost effectiveness. When you speak about the best, MedicoExperts is the name you can trust on. Modern technology, state of the art hospitals, most coveted gynecologist and fertility specialists, excellent infrastructure at par with international standards, no language barrier, personalized attention, safe surgery and seamless travel are some of our zeniths which magnetizes individuals worldwide to get their Infertility Treatment in India done through us.

We are thus committed to offer you the best possible and special negotiated prices for your IVF treatment without compromising on the quality of medical services and results. Here’s a look at the approximate costs of IVF treatment in India:

Sr.No. Procedures Cost of Procedure USD
1 IVF Evaluation Package 600-1000
2 In Vitro Fertilization (IVF) 3500-6000
3 In Vitro Fertilization (IVF) with Donor Egg 4500-7500
4 In Vitro Fertilization (IVF) with Donor Sperm 4500-7500
5 Intra Cytoplasmic Sperm Injection 3000-6000

Frequently Asked Questions and patient concerns:

1. What exactly is IVF?

In vitro fertilization (IVF) is a type of assisted reproductive technology (ART) that is commonly used to achieve pregnancy in couples who are experiencing infertility due to abnormal sperm count, issue with the fallopian tube or problems in ovulation.
In an IVF procedure, the eggs from a female are removed surgically, fertilized in a lab with the partners (or donors) sperm and then transferred back into the woman’s womb after a period of 2-5 days.

2. When should IVF be considered?

Women who face issues in pregnancy because of blocked or missing fallopian tubes can consider IVF as a choice of infertility treatment. Unexplained infertility, endometriosis, or male factor infertility can also be possible reasons to consider IVF.

3. How many days are required for IVF or ICSI treatment?

IVF or ICSI treatment requires about 30 days including the start of injections to the final transfer Treatment requires 30 days, from start of injection of down regulation to embryo transfer.

4. Is the process of transferring embryo painful?

No, the process is not painful. As no anesthesia is required during the transfer procedure, the woman will only feel the speculum that allows the doctor to view the cervix. The procedure is very similar to an intrauterine insemination (IUI).

5. Is bed rest recommended after the embryo transfer?

It is advised to reduce strenuous activities and relax on the day of the embryo transfer. Routine activities can be resumed the following day. However, strenuous activities can be minimized to avoid risk. We will recommend preventative bed rest if there is an increased risk of ovarian hyperstimulation.

6. How soon after IVF can a pregnancy test be performed?

A pregnancy test (which is a measurement of hCG hormone in the urine or blood) would be positive for a number of days after egg retrieval, as hCG is used to fertilize eggs. Some women will rapidly metabolize the hormone and in around a week it will be out of the blood stream, while others can take up to 9 or 10 days to do so. Therefore, we recommend that a pregnancy test should not be carried out until 12-14 days after the restoration of the eggs.

7. If an egg is not retrieved or if on the first try, the process does not yield a pregnancy, how quickly will the procedure be repeated?

This is entirely subjective. The primary reason for the delay is to allow the usual menstrual cycle of the woman to continue, which can take 2 to 3 cycles.

8. How long do we need to wait to have intercourse after the IVF procedure?

Although a definite abstinence period has not been defined to prevent pre-embryo damage, most experts recommend abstinence for two to three weeks. Theoretically, the early stages of implantation may interfere with the uterine contractions associated with orgasm. However, it is permissible to have intercourse the night before pre-embryo transfer. Before transfer, certain doctors will prescribe intercourse as they believe that this will increase the likelihood of a pregnancy.

9. When can I get back to my daily activities?

Following pre-embryo placement in the uterus, the IVF team suggests that the patient be sedentary for a complete 24 hours. Strenuous exercises should be avoided before pregnancy is confirmed, such as jogging, horseback riding, swimming, etc. However, the patient is free to resume daily routine.

10. Why does IVF fail at times?

IVF fails primarily for two reasons. One is due to egg quality and the second is implantation failure. These things can also happen in normal pregnancies, but as IVF entails costs, and therefore more stressful. Stimulation quality and embryology quality matter a lot, but by taking strict steps, these can be corrected, but egg quality and implantation are still beyond anyone’s approach.

11. Before choosing one, how do I rate fertility centers?

In general, retrieving or understanding the statistical data of an IVF center is crucial for every couple. This is most certainly achievable during a consultation. When you speak with our healthcare expert about your treatment regimen, ask for some new details to help you understand what you are dealing with. Similarly, try to assess your age, infertility issue, and expectations.

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